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A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells.

ABSTRACT: A new ratiometric fluorescent probe was constructed with hemicyanine and 7-nitrobenzofurazan for detection of sulfur dioxide derivatives (HSO3-/SO32-). The ratiometric response mode could be attributed to the efficient FRET (Förster resonance energy transfer) platform. The probe exbihited some desirable properties including fast response (within 2?minutes), good selectivity and high sensitivity. Moreover, the probe could detect endogenous HSO3- in liver cancer cells rather than normal liver cells, implying the diagnosal potential of the probe.

SUBMITTER: Li DP

PROVIDER: S-EPMC5368602 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature

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A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells.

Li Dong-Peng DP Wang Zhao-Yang ZY Cui Jie J Wang Xin X Miao Jun-Ying JY Zhao Bao-Xiang BX

Scientific reports 20170328

A new ratiometric fluorescent probe was constructed with hemicyanine and 7-nitrobenzofurazan for detection of sulfur dioxide derivatives (HSO3-/SO32-). The ratiometric response mode could be attributed to the efficient FRET (Förster resonance energy transfer) platform. The probe exbihited some desirable properties including fast response (within 2 minutes), good selectivity and high sensitivity. Moreover, the probe could detect endogenous HSO3</su ...[more]

PMID: 28349998

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