Unknown

Dataset Information

0

Asymmetric Copper Hydride-Catalyzed Markovnikov Hydrosilylation of Vinylarenes and Vinyl Heterocycles.


ABSTRACT: We report a highly enantioselective CuH-catalyzed Markovnikov hydrosilylation of vinylarenes and vinyl heterocycles. This method has a broad scope and enables both the synthesis of isolable silanes and the conversion of crude products to chiral alcohols. Density functional theory calculations support a mechanism proceeding by hydrocupration followed by σ-bond metathesis with a hydrosilane.

SUBMITTER: Gribble MW 

PROVIDER: S-EPMC5386394 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC5873224 | biostudies-other
| S-EPMC5992098 | biostudies-literature
| S-EPMC6020754 | biostudies-literature
| S-EPMC7875507 | biostudies-literature
| S-EPMC6641774 | biostudies-literature
| S-EPMC4127133 | biostudies-literature
| S-EPMC6972613 | biostudies-literature
| S-EPMC6261526 | biostudies-literature
| S-EPMC6858512 | biostudies-literature
| S-EPMC3296363 | biostudies-literature