Ontology highlight
ABSTRACT:
SUBMITTER: Ose J
PROVIDER: S-EPMC5447004 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Ose Jennifer J Schock Helena H Poole Elizabeth M EM Lehtinen Matti M Visvanathan Kala K Helzlsouer Kathy K Buring Julie E JE Lee I-Min IM Tjønneland Anne A Boutron-Ruault Marie-Christine MC Trichopoulou Antonia A Mattiello Amalia A Onland-Moret N Charlotte NC Weiderpass Elisabete E Sánchez María-José MJ Idahl Annika A Travis Ruth C RC Rinaldi Sabina S Merritt Melissa A MA Wentzensen Nicolas N Tworoger Shelley S SS Kaaks Rudolf R Fortner Renée T RT
Cancer causes & control : CCC 20170216 5
<h4>Purpose</h4>Biologic evidence suggests that the Insulin-like growth factor (IGF)-family may be involved in the etiology of epithelial invasive ovarian cancer (EOC). However, prospective studies investigating the role of IGF-I in ovarian carcinogenesis have yielded conflicting results.<h4>Methods</h4>We pooled and harmonized data from 6 case-control studies nested within the Ovarian Cancer Cohort Consortium to investigate the association between pre-diagnosis IGF-I concentrations and subseque ...[more]