Ontology highlight
ABSTRACT:
SUBMITTER: Bompard A
PROVIDER: S-EPMC5533793 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Bompard Anais A Da Dari F DF Yerbanga Rakiswendé S RS Biswas Sumi S Kapulu Melissa M Bousema Teun T Lefèvre Thierry T Cohuet Anna A Churcher Thomas S TS
Scientific reports 20170728 1
Transmission blocking vaccines (TBV) which aim to control malaria by inhibiting human-to-mosquito transmission show considerable promise though their utility against naturally circulating parasites remains unknown. The efficacy of two lead candidates targeting Pfs25 and Pfs230 antigens to prevent onwards transmission of naturally occurring parasites to a local mosquito strain is assessed using direct membrane feeding assays and murine antibodies in Burkina Faso. The transmission blocking activit ...[more]