Ontology highlight
ABSTRACT:
SUBMITTER: Menon V
PROVIDER: S-EPMC5780346 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Menon Vinay V Kapulu Melissa C MC Taylor Iona I Jewell Kerry K Li Yuanyuan Y Hill Fergal F Long Carole A CA Miura Kazutoyo K Biswas Sumi S
Frontiers in immunology 20180119
A malaria transmission-blocking vaccine would be a critical tool in achieving malaria elimination and eradication. By using chimpanzee adenovirus serotype 63 and modified vaccinia virus Ankara viral vectored vaccines, we investigated whether incorporating two antigens into one vaccine would result in higher transmission-reducing activity than one antigen. We demonstrated that when Pfs25 was administered with other antigens Pfs28 or Pfs230C, either concurrently as a mixed vaccine or co-expressed ...[more]