Ontology highlight
ABSTRACT:
SUBMITTER: Toro N
PROVIDER: S-EPMC5541045 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Toro Nicolás N Martínez-Abarca Francisco F González-Delgado Alejandro A
Scientific reports 20170802 1
CRISPR (clustered regularly interspaced short palindromic repeats) and associated proteins (Cas) act as adaptive immune systems in bacteria and archaea. Some CRISPR-Cas systems have been found to be associated with putative reverse transcriptases (RT), and an RT-Cas1 fusion associated with a type III-B system has been shown to acquire RNA spacers in vivo. Nevertheless, the origin and evolutionary relationships of these RTs and associated CRISPR-Cas systems remain largely unknown. We performed a ...[more]