Ontology highlight
ABSTRACT:
SUBMITTER: Bowles RD
PROVIDER: S-EPMC5627607 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Bowles Robert D RD Setton Lori A LA
Biomaterials 20170315
The intervertebral disc contributes to motion, weight bearing, and flexibility of the spine, but is susceptible to damage and morphological changes that contribute to pathology with age and injury. Engineering strategies that rely upon synthetic materials or composite implants that do not interface with the biological components of the disc have not met with widespread use or desirable outcomes in the treatment of intervertebral disc pathology. Here we review bioengineering advances to treat dis ...[more]