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Directed nucleophilic addition of phenoxides to cyclopropenes.

ABSTRACT: The alkali metal-templated addition of aryloxides across the double bond of non-conjugated cyclopropenes is described. High cis-selectivity is achieved through a directing effect of a strategically positioned carboxamide functionality.

SUBMITTER: Yamanushkin P

PROVIDER: S-EPMC5629095 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature

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Directed nucleophilic addition of phenoxides to cyclopropenes.

Yamanushkin Pavel P Lu-Diaz Michael M Edwards Andrew A Aksenov Nicolai A NA Rubina Marina M Rubin Michael M

Organic & biomolecular chemistry 20171001 38

The alkali metal-templated addition of aryloxides across the double bond of non-conjugated cyclopropenes is described. High cis-selectivity is achieved through a directing effect of a strategically positioned carboxamide functionality. ...[more]

PMID: 28920624

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