Ontology highlight
ABSTRACT:
SUBMITTER: Qiu Z
PROVIDER: S-EPMC5642148 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Chemical science 20170810 10
We herein describe a palladium-catalyzed formal aromaticity transfer coupling reaction between phenols and pyrrolidines or indolines to generate the corresponding <i>N</i>-cyclohexyl pyrroles or indoles. In this transformation, the aromaticity of phenols is formally passed on to the pyrrolidine or indoline units. Substituted phenols thus can serve as latent cyclohexyl equivalents for the fast construction of various <i>N</i>-cyclohexyl pyrroles and indoles. ...[more]