Ontology highlight
ABSTRACT:
SUBMITTER: Elsayed MSA
PROVIDER: S-EPMC5646376 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Synthetic communications 20160916 23
A novel indolophenanthridine ring system has been synthesized via the Schiff base-homophthalic anhydride cyclization followed by thionyl chloride-mediated dehydrogenation and intramolecular Friedel-Crafts acylation. This adds to the array of heterocyclic systems that are available through the cycloaddition reaction of imines with cyclic dicarboxylic acid anhydrides. The cytotoxicities of the indolophenanthridines were investigated in human cancer cell cultures, and the results documented signifi ...[more]