Ontology highlight
ABSTRACT:
SUBMITTER: Yuan WJ
PROVIDER: S-EPMC5674023 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Yuan Wen-Juan WJ Ding Xiao X Wang Zhe Z Yang Bi-Juan BJ Li Xiao-Nian XN Zhang Yu Y Chen Duo-Zhi DZ Li Shun-Lin SL Chen Quan Q Di Ying-Tong YT Aisa Haji Akber HA Hao Xiao-Jiang XJ
Scientific reports 20171106 1
Rare ent-abietane-rosane diterpenoid heterodimers, Bisebracteolasins A and B (1 and 2, respectively), were isolated from the roots of Euphorbia ebracteolata Hayata. Their structures and absolute configurations were elucidated from spectroscopic data and X-ray diffraction analysis. Compounds 1 and 2 exhibited moderate cytotoxic effects against five cancer cell lines. Compound 1 showed more effective antiproliferative activities against human tumour cells, HL-60 and SMMC-7721, with IC<sub>50</sub> ...[more]