Ontology highlight
ABSTRACT:
SUBMITTER: Pierini S
PROVIDER: S-EPMC5706602 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Oncoimmunology 20171120 12
DNA-based vaccination is a promising approach to cancer immunotherapy. DNA-based vaccines specific for tumor-associated antigens (TAAs) are indeed relatively simple to produce, cost-efficient and well tolerated. However, the clinical efficacy of DNA-based vaccines for cancer therapy is considerably limited by central and peripheral tolerance. During the past decade, considerable efforts have been devoted to the development and characterization of novel DNA-based vaccines that would circumvent th ...[more]