Ontology highlight
ABSTRACT:
SUBMITTER: Benoit SW
PROVIDER: S-EPMC5723563 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Benoit Stefanie Woolridge SW Devarajan Prasad P
Pediatric nephrology (Berlin, Germany) 20170610 5
Acute kidney injury (AKI) is a significant source of morbidity and mortality in pediatric patients, affecting more than one quarter of critically ill children. Despite significant need, there are no targeted therapies to reliably prevent or treat AKI. Recent advances in our understanding of renal injury and repair signaling pathways have enabled the development of several targeted pharmaceuticals. Here we review emerging pharmacotherapies for AKI that are currently in clinical trials. Categorize ...[more]