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Chromatin dynamics during the differentiation of long-term hematopoietic stem cells to multipotent progenitors.


ABSTRACT: ATAC-seq provides genome-wide chromatin state in 3 cell types of hematopoietic stem/progenitor cells.Transcription factor cohorts are associated with dynamic changes of open chromatin during the differentiation of LT/ST-HSCs to MPPs.

SUBMITTER: Yu X 

PROVIDER: S-EPMC5737588 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature

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Chromatin dynamics during the differentiation of long-term hematopoietic stem cells to multipotent progenitors.

Yu Xiang X   Wu Chao C   Bhavanasi Dheeraj D   Wang Hong H   Gregory Brian D BD   Huang Jian J  

Blood advances 20170530 14


ATAC-seq provides genome-wide chromatin state in 3 cell types of hematopoietic stem/progenitor cells.Transcription factor cohorts are associated with dynamic changes of open chromatin during the differentiation of LT/ST-HSCs to MPPs. ...[more]

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