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Ensembl 2018.


ABSTRACT: The Ensembl project has been aggregating, processing, integrating and redistributing genomic datasets since the initial releases of the draft human genome, with the aim of accelerating genomics research through rapid open distribution of public data. Large amounts of raw data are thus transformed into knowledge, which is made available via a multitude of channels, in particular our browser (http://www.ensembl.org). Over time, we have expanded in multiple directions. First, our resources describe multiple fields of genomics, in particular gene annotation, comparative genomics, genetics and epigenomics. Second, we cover a growing number of genome assemblies; Ensembl Release 90 contains exactly 100. Third, our databases feed simultaneously into an array of services designed around different use cases, ranging from quick browsing to genome-wide bioinformatic analysis. We present here the latest developments of the Ensembl project, with a focus on managing an increasing number of assemblies, supporting efforts in genome interpretation and improving our browser.

SUBMITTER: Zerbino DR 

PROVIDER: S-EPMC5753206 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature

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Ensembl 2018.

Zerbino Daniel R DR   Achuthan Premanand P   Akanni Wasiu W   Amode M Ridwan MR   Barrell Daniel D   Bhai Jyothish J   Billis Konstantinos K   Cummins Carla C   Gall Astrid A   Girón Carlos García CG   Gil Laurent L   Gordon Leo L   Haggerty Leanne L   Haskell Erin E   Hourlier Thibaut T   Izuogu Osagie G OG   Janacek Sophie H SH   Juettemann Thomas T   To Jimmy Kiang JK   Laird Matthew R MR   Lavidas Ilias I   Liu Zhicheng Z   Loveland Jane E JE   Maurel Thomas T   McLaren William W   Moore Benjamin B   Mudge Jonathan J   Murphy Daniel N DN   Newman Victoria V   Nuhn Michael M   Ogeh Denye D   Ong Chuang Kee CK   Parker Anne A   Patricio Mateus M   Riat Harpreet Singh HS   Schuilenburg Helen H   Sheppard Dan D   Sparrow Helen H   Taylor Kieron K   Thormann Anja A   Vullo Alessandro A   Walts Brandon B   Zadissa Amonida A   Frankish Adam A   Hunt Sarah E SE   Kostadima Myrto M   Langridge Nicholas N   Martin Fergal J FJ   Muffato Matthieu M   Perry Emily E   Ruffier Magali M   Staines Dan M DM   Trevanion Stephen J SJ   Aken Bronwen L BL   Cunningham Fiona F   Yates Andrew A   Flicek Paul P  

Nucleic acids research 20180101 D1


The Ensembl project has been aggregating, processing, integrating and redistributing genomic datasets since the initial releases of the draft human genome, with the aim of accelerating genomics research through rapid open distribution of public data. Large amounts of raw data are thus transformed into knowledge, which is made available via a multitude of channels, in particular our browser (http://www.ensembl.org). Over time, we have expanded in multiple directions. First, our resources describe  ...[more]

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