Dataset Information

Ensembl 2020.

ABSTRACT: The Ensembl (https://www.ensembl.org) is a system for generating and distributing genome annotation such as genes, variation, regulation and comparative genomics across the vertebrate subphylum and key model organisms. The Ensembl annotation pipeline is capable of integrating experimental and reference data from multiple providers into a single integrated resource. Here, we present 94 newly annotated and re-annotated genomes, bringing the total number of genomes offered by Ensembl to 227. This represents the single largest expansion of the resource since its inception. We also detail our continued efforts to improve human annotation, developments in our epigenome analysis and display, a new tool for imputing causal genes from genome-wide association studies and visualisation of variation within a 3D protein model. Finally, we present information on our new website. Both software and data are made available without restriction via our website, online tools platform and programmatic interfaces (available under an Apache 2.0 license) and data updates made available four times a year.

SUBMITTER: Yates AD

PROVIDER: S-EPMC7145704 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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Publications

Ensembl 2020.

Yates Andrew D AD Achuthan Premanand P Akanni Wasiu W Allen James J Allen Jamie J Alvarez-Jarreta Jorge J Amode M Ridwan MR Armean Irina M IM Azov Andrey G AG Bennett Ruth R Bhai Jyothish J Billis Konstantinos K Boddu Sanjay S Marugán José Carlos JC Cummins Carla C Davidson Claire C Dodiya Kamalkumar K Fatima Reham R Gall Astrid A Giron Carlos Garcia CG Gil Laurent L Grego Tiago T Haggerty Leanne L Haskell Erin E Hourlier Thibaut T Izuogu Osagie G OG Janacek Sophie H SH Juettemann Thomas T Kay Mike M Lavidas Ilias I Le Tuan T Lemos Diana D Martinez Jose Gonzalez JG Maurel Thomas T McDowall Mark M McMahon Aoife A Mohanan Shamika S Moore Benjamin B Nuhn Michael M Oheh Denye N DN Parker Anne A Parton Andrew A Patricio Mateus M Sakthivel Manoj Pandian MP Abdul Salam Ahamed Imran AI Schmitt Bianca M BM Schuilenburg Helen H Sheppard Dan D Sycheva Mira M Szuba Marek M Taylor Kieron K Thormann Anja A Threadgold Glen G Vullo Alessandro A Walts Brandon B Winterbottom Andrea A Zadissa Amonida A Chakiachvili Marc M Flint Bethany B Frankish Adam A Hunt Sarah E SE IIsley Garth G Kostadima Myrto M Langridge Nick N Loveland Jane E JE Martin Fergal J FJ Morales Joannella J Mudge Jonathan M JM Muffato Matthieu M Perry Emily E Ruffier Magali M Trevanion Stephen J SJ Cunningham Fiona F Howe Kevin L KL Zerbino Daniel R DR Flicek Paul P

Nucleic acids research 20200101 D1

The Ensembl (https://www.ensembl.org) is a system for generating and distributing genome annotation such as genes, variation, regulation and comparative genomics across the vertebrate subphylum and key model organisms. The Ensembl annotation pipeline is capable of integrating experimental and reference data from multiple providers into a single integrated resource. Here, we present 94 newly annotated and re-annotated genomes, bringing the total number of genomes offered by Ensembl to 227. This r ...[more]

PMID: 31691826

Dataset Information

Ensembl 2020.

Publications

Ensembl 2020.

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