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Dissemination of Multidrug-Resistant Proteus mirabilis Clones Carrying a Novel Integron-Borne blaIMP-1 in a Tertiary Hospital.

ABSTRACT: This study aimed to characterize multidrug-resistant Proteus mirabilis clones carrying a novel class 1 integron-borne blaIMP-1 In1359 was inserted into a large conjugative plasmid that also carried blaCTX-M-2 The production of carbapenemases in Enterobacteriaceae that are intrinsically resistant to polymyxins and tigecycline is very worrisome, representing a serious challenge to clinicians and infection control teams.

SUBMITTER: Ramos AC

PROVIDER: S-EPMC5786801 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature

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Dissemination of Multidrug-Resistant Proteus mirabilis Clones Carrying a Novel Integron-Borne blaIMP-1 in a Tertiary Hospital.

Ramos Ana Carolina AC Cayô Rodrigo R Carvalhaes Cecilia Godoy CG Jové Thomas T da Silva Greice Pereira GP Sancho Fernanda Maciel Paschoin FMP Chagas-Neto Thomas T Medeiros Eduardo Alexandrino Servolo EAS Gales Ana Cristina AC

Antimicrobial agents and chemotherapy 20180125 2

This study aimed to characterize multidrug-resistant Proteus mirabilis clones carrying a novel class 1 integron-borne blaIMP-1 In1359 was inserted into a large conjugative plasmid that also carried blaCTX-M-2 The production of carbapenemases in Enterobacteriaceae that are intrinsically resistant to polymyxins and tigecycline is very worrisome, representing a serious challenge to clinicians and infection control teams. ...[more]

PMID: 29158274

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