Ontology highlight
ABSTRACT: Software availability
AMARETTO is available as an R package at https://bitbucket.org/gevaertlab/pancanceramaretto.
SUBMITTER: Champion M
PROVIDER: S-EPMC5828545 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Champion Magali M Brennan Kevin K Croonenborghs Tom T Gentles Andrew J AJ Pochet Nathalie N Gevaert Olivier O
EBioMedicine 20171201
The availability of increasing volumes of multi-omics profiles across many cancers promises to improve our understanding of the regulatory mechanisms underlying cancer. The main challenge is to integrate these multiple levels of omics profiles and especially to analyze them across many cancers. Here we present AMARETTO, an algorithm that addresses both challenges in three steps. First, AMARETTO identifies potential cancer driver genes through integration of copy number, DNA methylation and gene ...[more]