Ontology highlight
ABSTRACT:
SUBMITTER: Pavankumar TL
PROVIDER: S-EPMC5854184 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Pavankumar T L TL Exell J C JC Kowalczykowski S C SC
Methods in enzymology 20161018
The unique translocation and DNA unwinding properties of DNA helicases can be concealed by the stochastic behavior of enzyme molecules within the necessarily large populations used in ensemble experiments. With recent technological advances, the direct visualization of helicases acting on individual DNA molecules has contributed significantly to the current understanding of their mechanisms of action and biological functions. The combination of single-molecule techniques that enable both manipul ...[more]