Ontology highlight
ABSTRACT:
SUBMITTER: Zhang F
PROVIDER: S-EPMC5870768 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Zhang Feng F Lu Yulan Y Yan Sijia S Xing Qinghe Q Tian Weidong W
Bioinformatics (Oxford, England) 20171101 22
<h4>Motivation</h4>RNA editing generates post-transcriptional sequence alterations. Detection of RNA editing sites (RESs) typically requires the filtering of SNVs called from RNA-seq data using an SNP database, an obstacle that is difficult to overcome for most organisms.<h4>Results</h4>Here, we present a novel method named SPRINT that identifies RESs without the need to filter out SNPs. SPRINT also integrates the detection of hyper RESs from remapped reads, and has been fully automated to any R ...[more]