Ontology highlight
ABSTRACT:
SUBMITTER: Ribeiro MFSA
PROVIDER: S-EPMC5914121 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Ribeiro Maurício Fernando Silva Almeida MFSA de Sousa Micelange Carvalho MC Hanna Samir Abdallah SA Maldaun Marcos Vinicius Calfat MVC Kurimori Ceci Obara CO de Lima Luiz Guilherme Cernaglia Aureliano LGCA Mattedi Romulo Loss RL Munhoz Rodrigo Ramella RR
Case reports in oncological medicine 20180410
<h4>Introduction</h4>Chordomas are rare malignancies of bone origin that occur in the axial skeleton, typically the skull base and lumbar/sacral regions. Although often classified as low-grade neoplasms, its locally infiltrative behavior may result in significant morbidity and mortality. Optimal surgical resection may be curative, but up to 50% of the cases relapse within 5 years, and currently there are no systemic treatments approved in this setting. A large proportion of these tumors express ...[more]