Ontology highlight
ABSTRACT:
SUBMITTER: Silveira MC
PROVIDER: S-EPMC5967600 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Silveira Melise Chaves MC Catanho Marcos M Miranda Antônio Basílio de AB
Memorias do Instituto Oswaldo Cruz 20180528 8
β-lactamases, which are found in several bacterial species and environments, are the main cause of resistance to β-lactams in Gram-negative bacteria. In 2009, a protein (LRA-13) with two β-lactamase domains (one class C domain and one class D domain) was experimentally characterised, and an extended action spectrum against β-lactams consistent with two functional domains was found. Here, we present the results of searches in the non-redundant NCBI protein database that revealed the existence of ...[more]