Ontology highlight
ABSTRACT:
SUBMITTER: Berens P
PROVIDER: S-EPMC5997358 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
PLoS computational biology 20180521 5
In recent years, two-photon calcium imaging has become a standard tool to probe the function of neural circuits and to study computations in neuronal populations. However, the acquired signal is only an indirect measurement of neural activity due to the comparatively slow dynamics of fluorescent calcium indicators. Different algorithms for estimating spike rates from noisy calcium measurements have been proposed in the past, but it is an open question how far performance can be improved. Here, w ...[more]