Ontology highlight
ABSTRACT:
SUBMITTER: Berens P
PROVIDER: S-EPMC5997358 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Berens Philipp P Freeman Jeremy J Deneux Thomas T Chenkov Nikolay N McColgan Thomas T Speiser Artur A Macke Jakob H JH Turaga Srinivas C SC Mineault Patrick P Rupprecht Peter P Gerhard Stephan S Friedrich Rainer W RW Friedrich Johannes J Paninski Liam L Pachitariu Marius M Harris Kenneth D KD Harris Kenneth D KD Bolte Ben B Machado Timothy A TA Ringach Dario D Stone Jasmine J Rogerson Luke E LE Sofroniew Nicolas J NJ Reimer Jacob J Froudarakis Emmanouil E Euler Thomas T Román Rosón Miroslav M Theis Lucas L Tolias Andreas S AS Bethge Matthias M
PLoS computational biology 20180521 5
In recent years, two-photon calcium imaging has become a standard tool to probe the function of neural circuits and to study computations in neuronal populations. However, the acquired signal is only an indirect measurement of neural activity due to the comparatively slow dynamics of fluorescent calcium indicators. Different algorithms for estimating spike rates from noisy calcium measurements have been proposed in the past, but it is an open question how far performance can be improved. Here, w ...[more]