Ontology highlight
ABSTRACT:
SUBMITTER: Iyer GR
PROVIDER: S-EPMC6016463 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Iyer Gayatri R GR Singh Shailja S Kaur Inderjeet I Agarwal Shalini S Siddiqui Mansoor A MA Bansal Abhisheka A Kumar Gautam G Saini Ekta E Paul Gourab G Mohmmed Asif A Chitnis Chetan E CE Malhotra Pawan P
The Journal of biological chemistry 20180501 25
The human malaria parasite <i>Plasmodium falciparum</i> proliferates in red blood cells following repeated cycles of invasion, multiplication, and egress. <i>P. falciparum</i> serine repeat antigen 5 (PfSERA5), a putative serine protease, plays an important role in merozoite egress. However, regulation of its activity leading to merozoite egress is poorly understood. In this study, we show that PfSERA5 undergoes phosphorylation prior to merozoite egress. Immunoprecipitation of parasite lysates u ...[more]