Ontology highlight
ABSTRACT:
SUBMITTER: Zhang H
PROVIDER: S-EPMC6017397 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Zhang Hengrui H Qin Nan N Fang Zhijie Z
Molecules (Basel, Switzerland) 20180222 2
A selective and ratiometric turn-on fluorescent probe was designed and synthesized by using a novel dicyanoisophorone-based derivative and acrylate moiety. The probe displayed high stability and good selectivity to cysteine (Cys) over homocysteine (Hcy) and glutathione (GSH). It also exhibited rapid response to Cys within 180 s. Most importantly, the fluorescence intensity ratio at 590 and 525 nm (I<sub>590</sub>/I<sub>525</sub>) was linearly dependent on the Cys concentration in the range from ...[more]