Ontology highlight
ABSTRACT:
SUBMITTER: Lee Y
PROVIDER: S-EPMC6070016 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Lee Yukyeong Y Kim C-Yoon CY Lee Hye Jeong HJ Kim Jae Gon JG Han Dong Wook DW Ko Kisung K Walter James J Chung Hyung-Min HM Schöler Hans R HR Bae Young Min YM Ko Kinarm K
Frontiers in cellular neuroscience 20180725
Oligodendrocyte progenitor cells (OPCs) are attracting attention as the ideal cell therapy for spinal cord injury (SCI). Recently, advanced reprogramming and differentiation techniques have made it possible to generate therapeutic cells for treating SCI. In the present study, we used directly-induced neural stem cells (DNSCs) from fibroblasts to establish OPCs (DN-OPCs) capable of proliferation and confirmed their OPC-specific characteristics. Also, we evaluated the effect of transplanted DN-OPC ...[more]