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Atom-Economic Synthesis of 4-Pyrones from Diynones and Water.

ABSTRACT: Transition-metal-free synthesis of 4-pyrones via TfOH-promoted nucleophilic addition/cyclization of diynones and water has been developed. This transformation is simple, atom economical and environmentally benign, providing rapid and efficient access to substituted 4-pyrones.

SUBMITTER: Xu YL

PROVIDER: S-EPMC6155647 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature

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Atom-Economic Synthesis of 4-Pyrones from Diynones and Water.

Xu Yan-Li YL Teng Qing-Hu QH Tong Wei W Wang Heng-Shan HS Pan Ying-Ming YM Ma Xian-Li XL

Molecules (Basel, Switzerland) 20170110 1

Transition-metal-free synthesis of 4-pyrones via TfOH-promoted nucleophilic addition/cyclization of diynones and water has been developed. This transformation is simple, atom economical and environmentally benign, providing rapid and efficient access to substituted 4-pyrones. ...[more]

PMID: 28075414

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