Dataset Information
Hydrogen sulfide increases glutathione biosynthesis, and glucose uptake and utilisation in C2C12 mouse myotubes.
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ABSTRACT:
SUBMITTER: Parsanathan R
PROVIDER: S-EPMC6181233 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Publications
Hydrogen sulfide increases glutathione biosynthesis, and glucose uptake and utilisation in C<sub>2</sub>C<sub>12</sub> mouse myotubes.
Free radical research 20180201 2
Diabetic patients have lower blood concentrations of hydrogen sulfide (H<sub>2</sub>S), L-cysteine (LC), and glutathione (GSH). Using C<sub>2</sub>C<sub>12</sub> mouse myotubes as a model, this study investigates the hypothesis that the beneficial effects of LC supplementation are mediated by upregulation of the H<sub>2</sub>S status under diabetic conditions. Results show that exogenous administration of sodium hydrosulfide (NaHS, 10 or 20 µM; 6 hours), a H<sub>2</sub>S donor, significantly (p ...[more]