Ontology highlight
ABSTRACT:
SUBMITTER: Liu J
PROVIDER: S-EPMC6232158 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Liu Jingmei J Han Ping P Gong Jin J Wang Yunwu Y Chen Bingxin B Liao Jiazhi J Tian Dean D
Cell death discovery 20181112
Accumulating evidence indicates that KIAA1199 plays a vital role in tumor progression. However, the role of KIAA1199 in hepatocellular carcinoma (HCC) still remains unknown. In this study, we found that KIAA1199 was upregulated in human HCC tissues and in highly metastatic HCC cell lines. Furthermore, the expression of KIAA1199 was significantly correlated with tumor size and metastasis in HCC. Knockdown of KIAA1199 inhibited cell proliferation and migration in vitro, and suppressed tumorigenici ...[more]