Ontology highlight
ABSTRACT:
SUBMITTER: Antoszczak M
PROVIDER: S-EPMC6271077 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Antoszczak Michał M Maj Ewa E Napiórkowska Agnieszka A Stefańska Joanna J Augustynowicz-Kopeć Ewa E Wietrzyk Joanna J Janczak Jan J Brzezinski Bogumil B Huczyński Adam A
Molecules (Basel, Switzerland) 20141125 12
A series of 12 novel monosubstituted N-benzyl amides of salinomycin (SAL) was synthesized for the first time and characterized by NMR and FT-IR spectroscopic methods. Molecular structures of three salinomycin derivatives in the solid state were determined using single crystal X-ray method. All compounds obtained were screened for their antiproliferative activity against various human cancer cell lines as well as against the most problematic bacteria strains such as methicillin-resistant Staphylo ...[more]