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Montmorillonite clay-promoted, solvent-free cross-aldol condensations under focused microwave irradiation.

ABSTRACT: An environmentally benign, clean and general protocol was developed for the synthesis of aryl and heteroaryl trans-chalcones. This method involved solvent-free reaction conditions under microwave irradiation in the presence of a clay-based catalyst, and afforded the target compounds in good yields and short reaction times. Furthermore, the same conditions allowed the synthesis of symmetrical, diarylmethylene-?,?-unsaturated ketones from aromatic aldehydes and ketones.

SUBMITTER: Rocchi D

PROVIDER: S-EPMC6271373 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature

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Montmorillonite clay-promoted, solvent-free cross-aldol condensations under focused microwave irradiation.

Rocchi Damiano D González Juan F JF Menéndez J Carlos JC

Molecules (Basel, Switzerland) 20140604 6

An environmentally benign, clean and general protocol was developed for the synthesis of aryl and heteroaryl trans-chalcones. This method involved solvent-free reaction conditions under microwave irradiation in the presence of a clay-based catalyst, and afforded the target compounds in good yields and short reaction times. Furthermore, the same conditions allowed the synthesis of symmetrical, diarylmethylene-α,β-unsaturated ketones from aromatic aldehydes and ketones. ...[more]

PMID: 24901834

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