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A Simple and Efficient Synthesis of Highly Substituted Indeno[1,2-b]pyrrole and Acenaphtho[1,2-b]pyrrole Derivatives by Tandem Three-Component Reactions.

ABSTRACT: A green, convenient and tandem procedure for the efficient synthesis of highly substituted indeno[1,2-b]pyrrole and acenaphtho[1,2-b]pyrrole derivatives by domino three-component reaction of tryptamine/benzylamine, 1,3-dicarbonyl compounds and ninhydrin/ acenaphthenequinone is described. The significant features of this procedure were characterized by mild reaction conditions, high yields, operational simplicity and it being environmentally benign.

SUBMITTER: Tang X 

PROVIDER: S-EPMC6278260 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature

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A Simple and Efficient Synthesis of Highly Substituted Indeno[1,2-<i>b</i>]pyrrole and Acenaphtho[1,2-<i>b</i>]pyrrole Derivatives by Tandem Three-Component Reactions.

Tang Xiaodong X   Zhu Songlei S   Ma Ying Y   Wen Ren R   Cen Lanqi L   Gong Panwei P   Wang Jing J  

Molecules (Basel, Switzerland) 20181120 11

A green, convenient and tandem procedure for the efficient synthesis of highly substituted indeno[1,2-<i>b</i>]pyrrole and acenaphtho[1,2-<i>b</i>]pyrrole derivatives by domino three-component reaction of tryptamine/benzylamine, 1,3-dicarbonyl compounds and ninhydrin/ acenaphthenequinone is described. The significant features of this procedure were characterized by mild reaction conditions, high yields, operational simplicity and it being environmentally benign. ...[more]

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