Ontology highlight
ABSTRACT:
SUBMITTER: Sader F
PROVIDER: S-EPMC6362101 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Sader Fadi F Denis Jean-François JF Laref Hamza H Roy Stéphane S
Scientific reports 20190204 1
Axolotls have the amazing ability to regenerate. When compared to humans, axolotls display a very fast wound closure, no scarring and are capable to replace lost appendages perfectly. Understanding the signaling mechanism leading to this perfect healing is a key step to help develop regenerative treatments for humans. In this paper, we studied cellular pathways leading to axolotl limb regeneration. We focus on the wound closure phase where keratinocytes migrate to close the lesion site and how e ...[more]