Synthesis, mol-ecular and crystal structure of 1-(1,2-di-hydro-phthalazin-1-yl-idene)-2-[1-(thio-phen-2-yl)ethyl-idene]hydrazine.

ABSTRACT: The title compound, C₁₄H₁₂N₄S, was synthesized by the condensation reaction of hydralazine and 2-acetyl-thio-phene and during the reaction, a proton transfer from the imino nitro-gen atom to one of the endocylic nitro-gen atoms occurred. The compound crystallizes in the monoclinic crystal system with two independent mol-ecules (mol-ecules 1 and 2) in the asymmetric unit. In each mol-ecule, there is a slight difference in the orientation of the thio-phene ring with respect to phthalazine ring system, mol-ecule 1 showing a dihedral angle of 42.51?(1)° compared to 8.48?(1)° in mol-ecule 2. This implies an r.m.s deviation of 0.428?(1)?Å between the two mol-ecules for the 19 non-H atoms. The two independent mol-ecules are connected via two N-H?N hydrogen bonds, forming dimers which inter-act by two bifurcated ?-? stacking inter-actions to build tetra-meric motifs. The latter are packed in the ac plane via weak C-H?? inter-actions and along the b axis via C-H ?N and C-H?? inter-actions. This results a three-dimensional architecture with a tilted herringbone packing mode.

SUBMITTER: Majoumo-Mbe F 

PROVIDER: S-EPMC6362644 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature