Split-QF System for Fine-Tuned Transgene Expression in Drosophila.
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ABSTRACT:
SUBMITTER: Riabinina O
PROVIDER: S-EPMC6499530 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Publications
Split-QF System for Fine-Tuned Transgene Expression in <i>Drosophila</i>.
Riabinina Olena O Vernon Samuel W SW Dickson Barry J BJ Baines Richard A RA
Genetics 20190312 1
The Q-system is a binary expression system that works well across species. Here, we report the development and demonstrate the applications of a split-QF system that drives strong expression in <i>Drosophila</i>, is repressible by QS, and is inducible by a small nontoxic molecule (quinic acid). The split-QF system is fully compatible with existing split-GAL4 and split-LexA lines, thus greatly expanding the range of possible advanced intersectional experiments and anatomical, physiological, and b ...[more]
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