Ontology highlight
ABSTRACT:
SUBMITTER: Aliper AM
PROVIDER: S-EPMC6520014 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Aliper Alexander M AM Bozdaganyan Marine E ME Orekhov Philipp S PS Zhavoronkov Alex A Osipov Andreyan N AN
Aging 20190401 8
All living organisms are subject to the aging process and experience the effect of ionizing radiation throughout their life. There have been a number of studies that linked ionizing radiation process to accelerated aging, but comprehensive signalome analysis of both processes was rarely conducted. Here we present a comparative signaling pathway based analysis of the transcriptomes of fibroblasts irradiated with different doses of ionizing radiation, replicatively aged fibroblasts and fibroblasts ...[more]