Dataset Information
Adsorption of molybdenum by melanin.
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ABSTRACT: Background
Melanin is detectable in various sense organs including the skin in animals. It has been reported that melanin adsorbs toxic elements such as mercury, cadmium, and lead. In this study, we investigated the adsorption of molybdenum, which is widely recognized as a toxic element, by melanin.Methods
Molybdenum level of the mouse skin was measured by inductively coupled plasma mass spectrometry. The pigmentation level of murine skin was digitalized as the L* value by using a reflectance spectrophotometer. An in vitro adsorption assay was performed to confirm the interaction between molybdenum and melanin.Results
Our analysis of hairless mice with different levels of skin pigmentation showed that the level of molybdenum increased with an increase in the level of skin pigmentation (L* value). Moreover, our analysis by Spearman's correlation coefficient test showed a strong correlation (r?=?-?0.9441, p?ConclusionOur in vivo and in vitro results showed a new aspect of melanin as an adsorbent of molybdenum.
SUBMITTER: Chen W
PROVIDER: S-EPMC6525471 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Publications
Adsorption of molybdenum by melanin.
Environmental health and preventive medicine 20190517 1
<h4>Background</h4>Melanin is detectable in various sense organs including the skin in animals. It has been reported that melanin adsorbs toxic elements such as mercury, cadmium, and lead. In this study, we investigated the adsorption of molybdenum, which is widely recognized as a toxic element, by melanin.<h4>Methods</h4>Molybdenum level of the mouse skin was measured by inductively coupled plasma mass spectrometry. The pigmentation level of murine skin was digitalized as the L* value by using ...[more]
