Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Z
PROVIDER: S-EPMC6540742 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Zhang Zongyi Z Sun Menghan M Deng Jieping J Yu Jianhai J Yang Xuesong X Zhao Wei W Chen Guobing G Wang Pengcheng P
Frontiers in microbiology 20190522
Dengue (DENV) and Zika virus (ZIKV) are important <i>flaviviruses</i> in tropical and subtropical regions, causing severe Dengue Hemorrhagic Fever (DHF)/Dengue Shock Syndrome (DSS) and microcephaly, respectively. The infection of both viruses during pregnancy were reported with adverse fetal outcomes. To investigate the effects of ZIKV and DENV infections on fetal development, we established an infection model in chicken embryos. Compared with DENV-2, the infection of ZIKV significantly retarded ...[more]