Ontology highlight
ABSTRACT:
SUBMITTER: Yu Y
PROVIDER: S-EPMC6584386 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Yu Yu Y Lin Xingyan X Wang Qilin Q He Mingguang M Chau Ying Y
Bioengineering & translational medicine 20190501 2
Wet age-related macular degeneration (wet-AMD) is a leading cause of irreversible blindness. Current treatment of AMD requires monthly intravitreal injection, which is difficult to be implemented in many parts of the world. In recent years, controlled release of anti-vascular endothelial growth factor (VEGF) therapeutics has attracted intense research interest aiming to reduce the injection frequency to one or two times per year. In this study, we evaluated the in vivo pharmacokinetics and the l ...[more]