Early natural history of neotissue formation in tissue-engineered vascular grafts in a murine model.
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ABSTRACT:
SUBMITTER: Reinhardt JW
PROVIDER: S-EPMC6587105 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Publications
Early natural history of neotissue formation in tissue-engineered vascular grafts in a murine model.
Reinhardt James W JW Rosado Juan de Dios Ruiz JDR Barker Jenny C JC Lee Yong-Ung YU Best Cameron A CA Yi Tai T Zeng Qiang Q Partida-Sanchez Santiago S Shinoka Toshiharu T Breuer Christopher K CK
Regenerative medicine 20190501 5
<b>Aim:</b> To characterize early events in neotissue formation during the first 2 weeks after vascular scaffold implantation. <b>Materials & methods:</b> Biodegradable polymeric scaffolds were implanted as abdominal inferior vena cava interposition grafts in wild-type mice. <b>Results:</b> All scaffolds explanted at day 1 contained a platelet-rich mural thrombus. Within the first few days, the majority of cell infiltration appeared to be from myeloid cells at the peritoneal surface with modest ...[more]
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