Ontology highlight
ABSTRACT:
SUBMITTER: Hu W
PROVIDER: S-EPMC6589259 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Hu Wentao W Zhu Lin L Pei Weiwei W Pan Shuxian S Guo Ziyang Z Wu Anqing A Pei Hailong H Nie Jing J Li Bingyan B Furusawa Yoshiya Y Konishi Teruaki T Hei Tom K TK Zhou Guangming G
Oxidative medicine and cellular longevity 20190602
Radioresistance is the major obstacle in the radiotherapy of the malignant melanoma. Thus, it is of importance to increase the radiosensitivity of melanoma cells. In the present study, the radioresistant melanoma cell line OCM-1 with inducible overexpression of Ras-related C3 botulinum toxin substrate 2 was established based on a radiation-inducible early growth response gene (Egr-1) promoter. The effects of Ras-related C3 botulinum toxin substrate 2 overexpression on the radiosensitivity of mel ...[more]