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A comparative analysis of BCL-2 family.


ABSTRACT: The BCL-2 family is conserved in evolution and shares a BCL-2 homology domain. It promotes and inhibits apoptosis. It is also known that apoptosis has a major role in effective cancer treatment. Therefore, it is of interest to document information related to the BCL-2 family of proteins for analysis by prediction tools. Hence, insights from a prediction based comparative functional analysis of 108 genes in this family are documented.

SUBMITTER: Choudhury S 

PROVIDER: S-EPMC6599443 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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A comparative analysis of BCL-2 family.

Choudhury Shouhartha S  

Bioinformation 20190415 4


The BCL-2 family is conserved in evolution and shares a BCL-2 homology domain. It promotes and inhibits apoptosis. It is also known that apoptosis has a major role in effective cancer treatment. Therefore, it is of interest to document information related to the BCL-2 family of proteins for analysis by prediction tools. Hence, insights from a prediction based comparative functional analysis of 108 genes in this family are documented. ...[more]

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