Ontology highlight
ABSTRACT:
SUBMITTER: Ferronha T
PROVIDER: S-EPMC6619200 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Ferronha Tiago T Rabadán M Angeles MA Gil-Guiñon Estel E Le Dréau Gwenvael G de Torres Carmen C Martí Elisa E
The Journal of neuroscience : the official journal of the Society for Neuroscience 20130201 7
Neuroblastoma is an embryonic tumor derived from cells of the neural crest. Taking advantage of a newly developed neural crest lineage tracer and based on the hypothesis that the molecular mechanisms that mediate neural crest delamination are also likely to be involved in the spread of neuroblastoma, we were able to identify genes that are active both in neural crest development and neuroblastoma tumor formation. A subsequent search of the neuroblastoma gene server for human orthologues of genes ...[more]