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Enantioselective PCCP Bronsted acid-catalyzed aza-Piancatelli rearrangement.

ABSTRACT: An enantioselective aza-Piancatelli rearrangement has been developed using a chiral Brønsted acid based on pentacarboxycyclopentadiene (PCCP). This reaction provides rapid access to valuable chiral 4-amino-2-cyclopentenone building blocks from readily available starting material and is operationally simple.

SUBMITTER: Hammersley GR

PROVIDER: S-EPMC6633596 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Enantioselective PCCP Brønsted acid-catalyzed aza-Piancatelli rearrangement.

Hammersley Gabrielle R GR Nichol Meghan F MF Steffens Helena C HC Delgado Jose M JM Veits Gesine K GK Read de Alaniz Javier J

Beilstein journal of organic chemistry 20190712

An enantioselective aza-Piancatelli rearrangement has been developed using a chiral Brønsted acid based on pentacarboxycyclopentadiene (PCCP). This reaction provides rapid access to valuable chiral 4-amino-2-cyclopentenone building blocks from readily available starting material and is operationally simple. ...[more]

PMID: 31354876

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