Ontology highlight
ABSTRACT:
SUBMITTER: Knighton RC
PROVIDER: S-EPMC6648819 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
ACS omega 20190129 1
The novel "double strained alkyne" <b>3</b> has been prepared and evaluated in strain-promoted azide-alkyne cycloaddition reactions with azides. The X-ray crystallographic structure of <b>3</b>, which was prepared in one step from 1,1'-biphenyl-2,2',6,6'-tetrol <b>4</b>, reveals the strained nature of the alkynes. Dialkyne <b>3</b> undergoes cycloaddition reactions with a number of azides, giving mixtures of regiosiomeric products in excellent yields. The monoaddition products were not observed ...[more]