Ontology highlight
ABSTRACT:
SUBMITTER: Coleman SK
PROVIDER: S-EPMC6674648 | biostudies-literature | 2006 Oct
REPOSITORIES: biostudies-literature
Coleman Sarah K SK Möykkynen Tommi T Cai Chunlin C von Ossowski Lotta L Kuismanen Esa E Korpi Esa R ER Keinänen Kari K
The Journal of neuroscience : the official journal of the Society for Neuroscience 20061001 43
Flip and flop splice variants of AMPA receptor subunits are expressed in distinct but partly overlapping patterns and impart different desensitization kinetics to cognate receptor channels. In the absence of specific antibodies, isoform-specific differences in trafficking or localization of native flip and flop subunits remain uncharacterized. We report that in several transfected cell lines, transport of homomeric glutamate receptor (GluR)-D(flop) receptors is largely blocked at the endoplasmic ...[more]