Ontology highlight
ABSTRACT:
SUBMITTER: Bos I
PROVIDER: S-EPMC6756978 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Bos Isabelle I Vos Stephanie J B SJB Schindler Suzanne E SE Hassenstab Jason J Xiong Chengjie C Grant Elizabeth E Verhey Frans F Morris John C JC Visser Pieter Jelle PJ Fagan Anne M AM
Alzheimer's & dementia : the journal of the Alzheimer's Association 20190801 9
<h4>Introduction</h4>Vascular factors increase the risk of Alzheimer's disease (AD). We investigated the associations between such factors, longitudinal AD cerebrospinal fluid biomarkers, and cognition.<h4>Methods</h4>433 cognitively normal participants were classified into four biomarker groups using their baseline amyloid (A+/-) and tau status (T+/-). 184 participants had undergone serial cerebrospinal fluid collection. Frequencies of risk factors and the Framingham Risk Score (FRS) were compa ...[more]