Ontology highlight
ABSTRACT:
SUBMITTER: Bonne-Annee S
PROVIDER: S-EPMC6778123 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Bonne-Année Sandra S Bush Mabel C MC Nutman Thomas B TB
Scientific reports 20191004 1
Using multiparameter flow cytometry human innate lymphoid cell (ILC) subsets can be detected in the circulation, in relatively low frequencies. Despite the low frequency of ILCs in circulation, ex vivo experiments have demonstrated that these ILCs release extremely large per cell quantities of signature ILC cytokines following activation. To determine how activated ILC cytokine production is regulated, ILC subsets were activated in the presence or absence of the immunoregulatory cytokines IL-10 ...[more]