Ontology highlight
ABSTRACT:
SUBMITTER: Boger C
PROVIDER: S-EPMC6795074 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Böger Carolin C Hafner Anne-Sophie AS Schlichthärle Thomas T Strauss Maximilian T MT Malkusch Sebastian S Endesfelder Ulrike U Jungmann Ralf R Schuman Erin M EM Heilemann Mike M
Neurophotonics 20190701 3
In the brain, the strength of each individual synapse is defined by the complement of proteins present or the "local proteome." Activity-dependent changes in synaptic strength are the result of changes in this local proteome and posttranslational protein modifications. Although most synaptic proteins have been identified, we still know little about protein copy numbers in individual synapses and variations between synapses. We use DNA-point accumulation for imaging in nanoscale topography as a s ...[more]