Ontology highlight
ABSTRACT:
SUBMITTER: Demonbreun AR
PROVIDER: S-EPMC6819108 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Demonbreun Alexis R AR Fallon Katherine S KS Oosterbaan Claire C CC Bogdanovic Elena E Warner James L JL Sell Jordan J JJ Page Patrick G PG Quattrocelli Mattia M Barefield David Y DY McNally Elizabeth M EM
The Journal of clinical investigation 20191101 11
Membrane repair is essential to cell survival. In skeletal muscle, injury often associates with plasma membrane disruption. Additionally, muscular dystrophy is linked to mutations in genes that produce fragile membranes or reduce membrane repair. Methods to enhance repair and reduce susceptibility to injury could benefit muscle in both acute and chronic injury settings. Annexins are a family of membrane-associated Ca2+-binding proteins implicated in repair, and annexin A6 was previously identifi ...[more]